Dr. Counter is a Professor in the departments of Pharmacology & Cancer Biology and in Radiation Oncology as well as serving as the Associate Director of Basic Research in the Duke Cancer Institute and Adjunct Professor at Duke-NUS. His laboratory studies the molecular mechanisms underlying the evolution of normal cells into cancer. His research has shown that the ability of cancer cells to become immortal is a fundamental aspect of tumorigenesis. His laboratory exploited this feature to recreate and study the tumorigenic process, particularly with regards to early mutations initiating tumorigenesis.