Sheng-Yang He is a Professor of Biology at Duke University and an Investigator at Howard Hughes Medical institute. His lab uses Pseudomonas syringae infection of Arabidopsis thaliana as a model to discover basic principles that govern bacterial pathogenesis and disease susceptibility in plants. Results from his lab in the past 25 years have led to foundational insights into processes that govern plant-pathogen interactions, including plant immunity, bacterial virulence, jasmonate hormone signaling and epidermal stomatal defense. Recent research in his lab begins to shed light on how climate conditions influence infectious diseases and how plants regulate microbiota homeostasis to prevent dysbiosis. Dr. He received his Bachelor’s and Master’s degrees from Zhejiang University, China, and a PhD degree from Cornell University, USA. He is a Thomson Reuters Highly Cited Researcher, a Past-President of the International Society of Molecular Plant-Microbe Interactions, a fellow of the American Association for the Advancement of Science and a member of the United States National Academy of Sciences.